B Complex with Metafolin offers the benefits of B vitamins combined with Metafolin, an active form of folic acid and may help relieve anxiety and adrenal fatigue. B vitamins play an important role in energy production. They are important for blood cells, hormones and nervous system functions. With the exception of B-12, they are not stored in the body in large amounts because they are water-soluble. So the body needs to replenish its B vitamins daily. Take B Complex with Metafolin to help your body try to maintain the right supply of B vitamins it needs.
- Technical Specs
B Complex with Metafolin® may be useful for individuals who want to supplement with a complete array of B vitamins and related nutrients.
Ingredients / Formula
One vegetarian capsule contains:
- Thiamine (Vitamin B-1, as thiamine HCL) 50 mg
- Riboflavin (Vitamin B-2, Riboflavin-5-Phosphate) 20 mg
- Niacin (Vitamin B-3, as Niacinamide) 50 mg
- Vitamin B-6 (as Pyridoxal-5 Phosphate) 20 mg
- Folate (as 5-MTHF, Metafolin®). 400 mcg
- Vitamin B-12 (as methylcobalamin) 500 mcg
- Biotin 300 mcg
- Pantothenic Acid (Vitamin B-5, as d-calcium pantothenate) 50 mg
- Intrinsic Factor (from porcine) 20 mg
Adults take 1 capsule, one to two times daily or as directed by a healthcare professional.
No adverse side effects have been reported.
Store in a cool, dry place, away from direct light. Keep out of reach of children.
- Extended Information
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Quadros EV Br J Haematol. Advances in the understanding of cobalamin assimilation and metabolism. 2010 Jan;148(2):195-204. Epub 2009 Oct 12. Review.
Hvas AM, Buhl H, Laursen NB, Hesse B, Berglund L, Nexo E.Haematologica. The effect of recombinant human intrinsic factor on the uptake of vitamin B12 in patients with evident vitamin B12 deficiency.Jun;91(6):805-8. Epub 2006 May 16.
Pietrzik K, Bailey L, Shane B. Folic acid and L-5-methyltetrahydrofolate: comparison of clinical pharmacokinetics and pharmacodynamics. Clin Pharmacokinet. 2010 Aug 1;49(8):535-48
Mahadeo KM, Min SH, Diop-Bove N, Kronn D, Goldman ID. Hereditary Folate Malabsorption. In: Pagon RA, Bird TC, Dolan CR, Stephens K, editors. GeneReviews [Internet]. Seattle (WA): University of Washington, Seattle; 1993-.2008 Jun 17 [updated 2010 May 06].
Helga Refsum and Keith M. Channon de Bono, Justin Lee, Paul Leeson, Stefan Neubauer, Chandi Ratnatunga, Ravi Pillai, Charalambos Antoniades, Cheerag Shirodaria, Nicholas Warrick, Shijie Cai, Joseph.
5-Methyltetrahydrofolate Rapidly Improves Endothelial Function and Decreases Superoxide Production in Human Vessels: Effects on Vascular Coupling Tetrahydrobiopterin Availability and Endothelial Nitric Oxide Synthase . Circulation 2006;114;1193-1201; originally published online Aug 28, 2006
Andersen CB, Madsen M, Storm T, Moestrup SK, Andersen GR. Structural basis for receptor recognition of vitamin-B(12)-intrinsic factor complexes. Nature. 2010 Mar 18;464(7287):445-8